Downtown, Midtown, Uptown

So Manhattan has downtown, midtown, and uptown. Chicago has the loop (downtown) and uptown, but I'm not aware of any midtown (correct me if I'm wrong Chicagoans) Atlanta has downtown and midtown but I dont know of any uptown (again correct me if I'm wrong. Then Charlotte calls its CBD Uptown. Does your city have a midtown/uptown. If so what characterizes it and sets it apart from "downtown"Is it just because that district is north of downtown following the Chicago/NYC model or are there other reasons. I know next to nothing on this subject but am curious. So please pardon my ignorance if any of the information above is incorrect.>